CVTree3: Composition Vector Tree Version 3

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CVTree constructs whole-genome based phylogenetic trees without sequence alignment by using a Composition Vector (CV) approach. It was first developed to infer evolutionary relatedness of microbial organisms and then successfully applied to viruses, chloroplasts, and fungi. CVTree3 makes comparison with taxonomy and reports tree-branch monophyleticity from domain to species. Please read the Online User's Manual PDF edition for details.

Ji Qi, Bin Wang, Bailin Hao (2004) Whole proteome prokaryote phylogeny without sequence alignment: a K-string composition approach, J Mol Evol, 58: 1 –11
Guanghong Zuo, Bailin Hao (2015) CVTree3 web server for whole-genome-based and alignment-free prokaryotic phylogeny and taxonomy, Genomics Proteomics & Bioinformatics, 13: 321-331.
Load/Create Project:
Enter Project Number to reload a previously completed project for checking or changing parameters and re-run. A blank input creates a new project. A project will be kept for 7 days after the last run.
A new CVTree server with more than 100,000 inbuilt genomes is online now. Please try it here