CVTree4: Composition Vector Tree Version 4

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CVTree constructs whole-genome based phylogenetic trees without sequence alignment by using a Composition Vector (CV) approach. It was first developed to infer evolutionary relatedness of microbial organisms and then successfully applied to viruses, chloroplasts, and fungi. CVTree3 makes comparison with taxonomy and reports tree-branch monophyleticity from domain to species. Please read the Online User's Manual PDF edition for details.

Guanghong Zuo (2021) CVTree: A Parallel Alignment-free Phylogeny and Taxonomy Tool based on Composition Vectors of Genomes, Genomics Proteomics & Bioinformatics, doi:10.1016/j.gpb.2021.03.006
Guanghong Zuo, Bailin Hao (2015) CVTree3 web server for whole-genome-based and alignment-free prokaryotic phylogeny and taxonomy, Genomics Proteomics & Bioinformatics, 13: 321-331.
Ji Qi, Bin Wang, Bailin Hao (2004) Whole proteome prokaryote phylogeny without sequence alignment: a K-string composition approach, J Mol Evol, 58: 1 –11
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